What Triggers Eosinophilic Gastritis

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14 Eyl 2023
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What Triggers Eosinophilic Gastritis?

Eosinophilic gastritis (EG) is a rare condition characterized by an overabundance of eosinophils, a type of white blood cell, in the stomach lining. Understanding the triggers for this condition is crucial for managing symptoms and preventing flare-ups.

1. Food Allergens

EG is often associated with food allergies or sensitivities. Common triggers include dairy, wheat, soy, eggs, and seafood. Individuals with EG may experience worsening symptoms after consuming these allergens.

2. Environmental Allergens

Exposure to environmental allergens such as pollen, dust mites, or animal dander can exacerbate EG symptoms. Allergic reactions to these triggers may lead to inflammation in the gastrointestinal tract, including the stomach.

3. Genetic Predisposition

Some individuals may have a genetic predisposition to EG, meaning they are more likely to develop the condition if other risk factors are present. Family history of allergic conditions or autoimmune disorders may increase the likelihood of EG.

4. Autoimmune Response

In some cases, EG may be triggered by an autoimmune response, where the body's immune system mistakenly attacks healthy tissues in the stomach lining. This immune dysregulation leads to inflammation and an increase in eosinophils.

5. Stress and Anxiety

Stress and anxiety can exacerbate symptoms of EG by affecting the immune system and digestive processes. Emotional stressors may trigger inflammation in the gastrointestinal tract, contributing to EG flare-ups.

6. Medications

Certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, and proton pump inhibitors (PPIs), have been associated with EG. These medications may disrupt the balance of immune cells in the stomach lining, leading to eosinophilic infiltration.

Conclusion

Identifying and avoiding triggers is essential for managing eosinophilic gastritis and reducing symptom severity. Individuals with EG should work closely with healthcare providers to develop personalized treatment plans that address trigger factors and promote gastrointestinal health. By addressing triggers and adopting lifestyle modifications, individuals with EG can better manage their condition and improve their quality of life.
 

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